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Associations between Aircraft Noise Exposure and Self-Reported Sleep Duration and Quality in the United States-Based Prospective Nurses’ Health Study Cohort Matthew Bozigar,1* Tianyi Huang,2 Susan Redline,2,3,4 Jaime E. Hart,2,5 Stephanie T. Grady,1 Daniel D. Nguyen,1 Peter James,5,6 Bradley Nicholas,7 Jonathan I. Levy,1 Francine Laden,2,3,5 and Junenette L. Peters1 1Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts, USA 2Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA 3Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA 4Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA 5Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA 6Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA 7Volpe National Transportation Systems Center, U.S. Department of Transportation, Cambridge, Massachusetts, USA BACKGROUND: Sleep disruption is linked with chronic disease, and aircraft noise can disrupt sleep. However, there are few investigations of aircraft noise and sleep in large cohorts. OBJECTIVES: We examined associations between aircraft noise and self-reported sleep duration and quality in the Nurses’ Health Study, a large pro- spective cohort. METHODS: Aircraft nighttime equivalent sound levels (Lnight) and day–night average sound levels (DNL) were modeled around 90 U.S. airports from 1995 to 2015 in 5-y intervals using the Aviation Environmental Design Tool and linked to geocoded participant residential addresses. Lnight ex- posure was dichotomized at the lowest modeled level of 45 A-weighted decibels [dB(A)] and at multiple…

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